Tante Girang Tajir Asia Hot Drug substances of central nervous system: 1. Aminofenazon: aminopyrin (Fi), amidopyrin, Pyramidon. Derivatives-this pirazolinon (1887) analgetis efficacious, antipiretis and anti-inflammatory. Resorpsinya in the intestines quickly, began its work after 30-45 minutes, plasma-t1/2-nya 2-7 hours. Because of its side effects on the blood (agranulocytosis, leukopenia) is often fatal, this drug has been since the 1980's banned its circulation in many countries. When the resulting small ulcers in the mouth, sore throat or fever (signs of agranulocytosis), treatment should be stopped immediately! Pregnancy and lactation. All drugs of pirazolinon group should not be used during pregnancy and lactation. Dosage: 300-600 mg 3 dd, maximum 3 g / day.
Use: These medications can relieve or eliminate pain without affecting the CNS or lose consciousness, also does not cause addiction. Most of these substances are also helpless antipiretis and / or anti-inflammatory. It is therefore not only used as a drug antinyeri, but also at a fever (a viral infection / germs, colds, runny nose) and inflammation such as rheumatism and gout. These drugs are often given for mild to moderate pain, which causes diverse, such as headache, teeth, muscles or joints (Rema, gout), stomach, menstrual pain (dystnenorroe), pain due to collision or accident (trauma). For the second last pain, NSAIDs are more feasible. In more severe pain eg. after surgery or fracture (broken bone), it works less potent.